The Real-Time Biosurveillance Program (RTBP) information communication system comprises an upstream health data submission by last-mile health workers, data processing by epidemiologist, and downstream alerting by health officials.There are four components to the RTBP software: mobile phone application, desktop web application, database, T-Cube analytic tools, and Common Alerting Protocol messaging. The individual components are to be developed by Rural Technology and Business Incubator, Respere (Private) Limited, and Auton Lab. Following are the four software requirement specification documents – 1) Sahana biosurveillance module (database and desktop web application) 2) Mobile J2ME application (data collection) 3) T-Cube web interface (analysis and event detection) 4) Sahana Common Alerting Protocol Messaging Module (publishing SMS/Email/Web alerts)