The IEEE-RIVF – Research, Innovation, and Vision for the Future – International Conference on Computing and Communication Technology took place in Hanoi, Vietnam at the Vietnam National University, Nov 02-04, 2010. The plannery sessions were on applied operations research, software engineering, human machine interface & imaging technology, computational Intelligence, information & knowledge management, communication & networking, and modeling & computer simulations. I presented out paper titled: T-Cube Web Interface as a Tool for detecting disease outbreaks in real-time: a pilot in India and Sri Lanka. This paper discusses the results from the pilot in India and Sri Lanka, namely the Real-Time Biosurveillance Program (RTBP). While may discussed the science behind their solutions, we had surpassed that and were able to discuss the challenges in practically working the solutions in the real world. Unfortunate, the uncertainties in the field, in an actual implementation with non technical people operating the system, are far greater than what we envision in the laboratory.